Human SUCNR1 Recombinant Protein (N-His-KSI) (HD131012)

Name: Human SUCNR1 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD131012
Price: 211 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HD131012
Descripción	Recombinant Human SUCNR1 Protein, N-His-KSI (HD131012) expressed in E. coli. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q9BXA5
Longitud de proteína	Leu2-Gly31&Arg81-His103&Pro159-Leu185&Tyr207-Pro230&Arg252-Arg281&Arg303-Lys334
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	35.81 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	G-protein coupled receptor 91, GPR91, P2Y purinoceptor 1-like, SUCNR1, Succinate receptor 1
Fondo	Succinate receptor 1 is a ~38 kDa protein. G protein-coupled receptor for succinate able to mediate signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and the processes regulated. Succinate-SUCNR1 signaling serves as a link between metabolic stress, inflammation and energy homeostasis. In macrophages, plays a range of immune-regulatory roles. During inflammation, succinate-SUCNR1 signaling may act as an anti-inflammatory mediator or boost inflammation depending on the inflammatory status of cells. Hyperpolarizes M2 macrophages versus M1 phenotype through Gq signaling by regulating the transcription of genes involved in immune function. 1. He, W. et al. (2004) Nature 429, 188-93. PMID: 15141213 2. Sundström, L. et al. (2013) FEBS letters 587, 2399-404. PMID: 23770096 3. Trauelsen, M. et al. (2021) Cell reports 35, 109246. PMID: 34133934 4. Rubic, T. et al. (2008) Nature immunology 9, 1261-9. PMID: 18820681
Nota	For research use only

Imágenes

Referencias

Datasheet

Human SUCNR1 Recombinant Protein (N-His-KSI).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo