Human SUCNR1 Recombinant Protein (N-His-KSI) (HD131012)

Name: Human SUCNR1 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD131012
Price: 211 USD
Availability: InStock

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Каталожный номер	HD131012
Описание	Recombinant Human SUCNR1 Protein, N-His-KSI (HD131012) expressed in E. coli. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q9BXA5
Длина белка	Leu2-Gly31&Arg81-His103&Pro159-Leu185&Tyr207-Pro230&Arg252-Arg281&Arg303-Lys334
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	35.81 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	G-protein coupled receptor 91, GPR91, P2Y purinoceptor 1-like, SUCNR1, Succinate receptor 1
Фон	Succinate receptor 1 is a ~38 kDa protein. G protein-coupled receptor for succinate able to mediate signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and the processes regulated. Succinate-SUCNR1 signaling serves as a link between metabolic stress, inflammation and energy homeostasis. In macrophages, plays a range of immune-regulatory roles. During inflammation, succinate-SUCNR1 signaling may act as an anti-inflammatory mediator or boost inflammation depending on the inflammatory status of cells. Hyperpolarizes M2 macrophages versus M1 phenotype through Gq signaling by regulating the transcription of genes involved in immune function. 1. He, W. et al. (2004) Nature 429, 188-93. PMID: 15141213 2. Sundström, L. et al. (2013) FEBS letters 587, 2399-404. PMID: 23770096 3. Trauelsen, M. et al. (2021) Cell reports 35, 109246. PMID: 34133934 4. Rubic, T. et al. (2008) Nature immunology 9, 1261-9. PMID: 18820681
Примечание	For research use only

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Human SUCNR1 Recombinant Protein (N-His-KSI).pdf

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