Human TBC1D5 Recombinant Protein (N-His) (HD136012)

Name: Human TBC1D5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD136012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD136012
Descripción	Recombinant Human TBC1D5 Protein, N-His (HD136012) expressed in E. coli, spanning Ser43-Ser266. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q92609
Longitud de proteína	Ser43-Ser266
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	28.86 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	KIAA0210, TBC1 domain family member 5, TBC1D5
Fondo	TBC1 domain family member 5 is a ~89 kDa protein. May act as a GTPase-activating protein (GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy. 1. Seaman, MN. et al. (2009) Journal of cell science 122, 2371-82. PMID: 19531583 2. Harbour, ME. et al. (2010) Journal of cell science 123, 3703-17. PMID: 20923837 3. Popovic, D. et al. (2012) Molecular and cellular biology 32, 1733-44. PMID: 22354992 4. Popovic, D. et al. (2014) EMBO reports 15, 392-401. PMID: 24603492
Nota	For research use only

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Referencias

Datasheet

Human TBC1D5 Recombinant Protein (N-His).pdf

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