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Human TBX2 Recombinant Protein (N-His) (HC745012)

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概要
カタログ番号HC745012
説明
Recombinant Human TBX2 Protein, N-His (HC745012) expressed in E. coli, spanning Glu102-Gly284. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムE. coli
アクセッション番号Q13207
タンパク質長Glu102-Gly284
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 23.59 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名T-box protein 2, T-box transcription factor TBX2, TBX2
背景

T-box transcription factor TBX2 is a ~75 kDa protein. Transcription factor which acts as a transcriptional repressor. May also function as a transcriptional activator. Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes. Required for cardiac atrioventricular canal formation. May cooperate with NKX2.5 to negatively modulate expression of NPPA/ANF in the atrioventricular canal.

1. Jacobs, JJ. et al. (2000) Nature genetics 26, 291-9. PMID: 11062467
2. Sinha, S. et al. (2000) Gene 258, 15-29. PMID: 11111039
3. Lingbeek, ME. et al. (2002) The Journal of biological chemistry 277, 26120-7. PMID: 12000749
4. Wang, B. et al. (2012) PloS one 7, e41355. PMID: 22844464
5. Reinhardt, S. et al. (2019) Cellular and molecular life sciences : CMLS 76, 1005-1025. PMID: 30599067
6. Liu, N. et al. (2018) Human molecular genetics 27, 2454-2465. PMID: 29726930
7. Martin, N. et al. (2012) The EMBO journal 31, 95-109. PMID: 22002537
注意事項 For research use only
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参考文献
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