Human TCF7L2 Recombinant Protein (N-His-SUMO & C-Strep) (HC177012)

Name: Human TCF7L2 Recombinant Protein (N-His-SUMO & C-Strep)
Brand: abinScience
SKU: HC177012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC177012
Descripción	Recombinant Human TCF7L2 Protein, N-His-SUMO & C-Strep (HC177012) expressed in E. coli, spanning Asn355-Lys425. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q9NQB0
Longitud de proteína	Asn355-Lys425
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	22.10 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	HMG box transcription factor 4, T-cell factor 4, T-cell-specific transcription factor 4, TCF-4, TCF4, TCF7L2, Transcription factor 7-like 2, hTCF-4
Fondo	Transcription factor 7-like 2 is a ~67 kDa protein. Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as a repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1.
Nota	For research use only

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Datasheet

Human TCF7L2 Recombinant Protein (N-His-SUMO & C-Strep).pdf

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