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| カタログ番号 | HC856012 |
|---|---|
| 説明 |
Recombinant Human TK2 Protein, N-His (HC856012) expressed in E. coli, spanning Ser51-Pro265. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O00142 |
| タンパク質長 | Ser51-Pro265 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 27.65 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | 2'-deoxyuridine kinase TK2, Deoxycytidine kinase TK2, EC:2.7.1.-, EC:2.7.1.21, EC:2.7.1.74, Mt-TK, TK2, Thymidine kinase 2, mitochondrial |
| 背景 | Thymidine kinase 2, mitochondrial is a ~31 kDa protein. Phosphorylates thymidine, deoxycytidine, and deoxyuridine in the mitochondrial matrix. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on TK2 and DGUOK. Widely used as target of antiviral and chemotherapeutic agents. 1. Saada, A. et al. (2001) Nature genetics 29, 342-4. PMID: 11687801 2. Wang, L. et al. (1999) FEBS letters 443, 170-4. PMID: 9989599 |
| 注意事項 | For research use only |
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