Human TRPV4 Recombinant Protein (N-His) (HC206012)

Name: Human TRPV4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC206012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HC206012
Описание	Recombinant Human TRPV4 Protein, N-His (HC206012) expressed in E. coli, spanning Arg151-Asn361. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q9HBA0
Длина белка	Arg151-Asn361
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	26.31 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	OTRPC4, Osm-9-like TRP channel 4, TRP12, TRPV4, Transient receptor potential cation channel subfamily V member 4, Transient receptor potential protein 12, TrpV4, VR-OAC, VRL-2, VRL2, VROAC, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, Vanilloid receptor-related osmotically-activated channel
Фон	Transient receptor potential cation channel subfamily V member 4 is a ~98 kDa protein. Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by heat, low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. 1. Arniges, M. et al. (2006) The Journal of biological chemistry 281, 1580-6. PMID: 16293632 2. Köttgen, M. et al. (2008) The Journal of cell biology 182, 437-47. PMID: 18695040 3. Garcia-Elias, A. et al. (2008) The Journal of biological chemistry 283, 31284-8. PMID: 18826956 4. Fiorillo, C. et al. (2012) Neurogenetics 13, 195-203. PMID: 22526352 5. Thorneloe, KS. et al. (2012) Science translational medicine 4, 159ra148. PMID: 23136043 6. Doñate-Macián, P. et al. (2018) Nature communications 9, 2307. PMID: 29899501
Примечание	For research use only

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Human TRPV4 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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