

| Número de catálogo | HD997012 |
|---|---|
| Descripción |
Recombinant Human TUSC3 Protein, N-His (HD997012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | Q13454 |
| Longitud de proteína | Gln42-Pro196 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Homo sapiens (Human) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3, Magnesium uptake/transporter TUSC3, N33, Oligosaccharyl transferase subunit TUSC3, Protein N33, TUSC3, Tumor suppressor candidate 3 |
| Fondo | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3 is a ~39 kDa protein. Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Also has oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. 1. Zhou, H. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 15750-5. PMID: 19717468 |
| Nota | For research use only |
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