Human TXK Recombinant Protein (N-His) (HD030012)

Name: Human TXK Recombinant Protein (N-His)
Brand: abinScience
SKU: HD030012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD030012
Descripción	Recombinant Human TXK Protein, N-His (HD030012) expressed in E. coli, spanning Ile85-Trp527. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P42681
Longitud de proteína	Ile85-Trp527
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	53.87 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	EC:2.7.10.2, PTK4, Protein-tyrosine kinase 4, RLK, Resting lymphocyte kinase, TXK, Tyrosine-protein kinase TXK
Fondo	Tyrosine-protein kinase TXK is a ~61 kDa protein. Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation leads to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420. Phosphorylation leads to TXK full activation. Also contributes to signaling from many receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. 1. Takeba, Y. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 2365-70. PMID: 11859127 2. Maruyama, T. et al. (2007) Clinical and experimental immunology 147, 164-75. PMID: 17177976
Nota	For research use only

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Datasheet

Human TXK Recombinant Protein (N-His).pdf

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