Human TYROBP Recombinant Protein (N-His) (HC157012)

Name: Human TYROBP Recombinant Protein (N-His)
Brand: abinScience
SKU: HC157012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HC157012
Description	Recombinant Human TYROBP Protein, N-His (HC157012) expressed in E. coli, spanning Leu22-Lys113. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	O43914
Longueur de protéine	Leu22-Lys113
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	12.34 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	DAP12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer-activating receptor-associated protein, TYRO protein tyrosine kinase-binding protein, TYROBP
Contexte	TYRO protein tyrosine kinase-binding protein is a ~12 kDa protein. Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors. TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation. Also has an inhibitory role in some cells. Non-covalently associates with activating receptors of the CD300 family to mediate cell activation. Also mediates cell activation through association with activating receptors of the CD200R family. 1. Dietrich, J. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 9-12. PMID: 10604985 2. Lanier, LL. et al. (1998) Nature 391, 703-7. PMID: 9490415 3. Lanier, LL. et al. (1998) Immunity 8, 693-701. PMID: 9655483 4. Nakano-Yokomizo, T. et al. (2011) The Journal of experimental medicine 208, 1661-71. PMID: 21727189 5. Aguilar, H. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6703-11. PMID: 15557162 6. Martínez-Barriocanal, A. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 2819-30. PMID: 16920917 7. Yamanishi, Y. et al. (2008) Blood 111, 688-98. PMID: 17928527 8. Niizuma, K. et al. (2015) The Journal of biological chemistry 290, 22298-308. PMID: 26221034 9. Bakker, AB. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9792-6. PMID: 10449773
Note	For research use only

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Human TYROBP Recombinant Protein (N-His).pdf

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