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| カタログ番号 | HC826012 |
|---|---|
| 説明 |
Recombinant Human UBA6 Protein, N-His (HC826012) expressed in E. coli, spanning Pro623-Gly888. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | A0AVT1 |
| タンパク質長 | Pro623-Gly888 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 32.87 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | E1-L2, EC:6.2.1.45, MOP-4, MOP4, Monocyte protein 4, UBA6, UBE1L2, Ubiquitin-activating enzyme 6, Ubiquitin-activating enzyme E1-like protein 2, Ubiquitin-like modifier-activating enzyme 6 |
| 背景 | Ubiquitin-like modifier-activating enzyme 6 is a ~117 kDa protein. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Also activates UBD/FAT10 conjugation via adenylation of its C-terminal glycine. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. 1. Truongvan, N. et al. (2022) Nature communications 13, 4789. PMID: 35970836 2. Yuan, L. et al. (2022) Nature communications 13, 4880. PMID: 35986001 3. Chiu, YH. et al. (2007) Molecular cell 27, 1014-23. PMID: 17889673 |
| 注意事項 | For research use only |
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