Human USP53 Recombinant Protein (N-His) (HD331012)

Name: Human USP53 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD331012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Обзор
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Обзор

Каталожный номер	HD331012
Описание	Recombinant Human USP53 Protein, N-His (HD331012) expressed in E. coli, spanning Ala27-Cys380. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q70EK8
Длина белка	Ala27-Cys380
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	42.73 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	EC:3.4.19.12, KIAA1350, USP53, Ubiquitin carboxyl-terminal hydrolase 53, Ubiquitin-specific peptidase 53
Фон	Ubiquitin carboxyl-terminal hydrolase 53 is a ~120 kDa protein. Deubiquitinase that mediates 'Lys-63'-linked deubiquitination of tight junction proteins, such as MARVELD2 and LSR, and which is involved in the survival of auditory hair cells and hearing. Specifically cleaves 'Lys-63'-linked polyubiquitin chains composed of at least 3 ubiquitin molecules, while it is not able to deubiquitinate substrates with shorter ubiquitin chains: recognizes ubiquitin chain in position S2 and catalyzes en bloc cleavage of polyubiquitin chains from substrate proteins. Probably acts by modulating the barrier properties and mechanical stability of tight junctions via deubiquitination of MARVELD2 and LSR. 1. Zhang, J. et al. (2020) Liver international : official journal of the International Association for the Study of the Liver 40, 1142-1150. PMID: 32124521 2. Wendrich, K. et al. (2025) Nature chemical biology 21, 746-757. PMID: 39587316
Примечание	For research use only

Изображения

SDS-PAGE

SDS-PAGE for Recombinant Human USP53 Protein, N-His

Ссылки

Даташит

Human USP53 Recombinant Protein (N-His).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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