

| Numéro de catalogue | HD082012 |
|---|---|
| Description |
Recombinant Human VSX2 Protein, N-His-KSI (HD082012) expressed in E. coli, spanning Thr2-Ala361. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | P58304 |
| Longueur de protéine | Thr2-Ala361 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 55.04 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CHX10, Ceh-10 homeodomain-containing homolog, HOX10, Homeobox protein CHX10, VSX2, Visual system homeobox 2 |
| Contexte | Visual system homeobox 2 is a ~39 kDa protein. Acts as a transcriptional regulator through binding to DNA at the consensus sequence 5'-[TC]TAATT[AG][AG]-3' upstream of gene promoters. Plays a significant role in the specification and morphogenesis of the sensory retina. May play a role in specification of V2a interneurons during spinal cord development. Mediates differentiation of V2a interneurons by repression of motor neuron gene transcription, via competitively binding to response elements that are activated by the ISL1-LHX3 complex, such as VSX1. Acts as a positive transcriptional regulator of NXNL1; regulation is significantly increased in synergy with VSX1. 1. Capowski, EE. et al. (2016) Stem cells (Dayton, Ohio) 34, 2625-2634. PMID: 27301076 2. Clark, AM. et al. (2008) Brain research 1192, 99-113. PMID: 17919464 3. Clovis, YM. et al. (2016) Cell reports 16, 1642-1652. PMID: 27477290 4. Dorval, KM. et al. (2006) The Journal of biological chemistry 281, 744-51. PMID: 16236706 |
| Note | For research use only |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский