Human WHR1 Recombinant Protein (N-His) (HD899012)

Name: Human WHR1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD899012
Price: 211 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HD899012
Descripción	Recombinant Human WHR1 Protein, N-His (HD899012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P49842
Longitud de proteína	Asp144-Thr254
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	G11, Inactive serine/threonine-protein kinase 19, Protein G11, Protein RP1, RP1, STK19, TWH19, Tandem winged helix protein formerly known as STK19, WHR1, Winged helix repair factor 1
Fondo	Winged helix repair factor 1 is a ~28 kDa protein. DNA-binding protein which is required for efficient transcription-coupled nucleotide excision repair (TC-NER). Acts as part of a TC-NER complex which assembles and interacts with RNA polymerase II (RNAPII) when it stalls at DNA lesions. TC-NER complex subunit UVSSA binds to the GTF2H1/p62 subunit of the TFIIH transcription factor complex, tethering TFIIH to the TC-NER complex. WHR1/STK19 then interacts with the XPD helicase subunit of TFIIH which guides TFIIH to DNA downstream of the stalled RNAPII, ensuring DNA repair. Directly interacts with RNAPII and also binds to downstream DNA. 1. Li, Y. et al. (2024) The Journal of cell biology 223. PMID: 38252411 2. Li, J. et al. (2024) Scientific reports 14, 14098. PMID: 38890355 3. Tan, Y. et al. (2024) Nucleic acids research 52, 12767-12783. PMID: 39353615 4. Ramadhin, AR. et al. (2024) Molecular cell 84, 4740-4757.e12. PMID: 39547223 5. Mevissen, TET. et al. (2024) Cell 187, 7091-7106.e24. PMID: 39547228 6. van den Heuvel, D. et al. (2024) Cell 187, 7107-7125.e25. PMID: 39547229
Nota	For research use only

Imágenes

Referencias

Datasheet

Human WHR1 Recombinant Protein (N-His).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo