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| カタログ番号 | HD388012 |
|---|---|
| 説明 |
Recombinant Human ZDHHC18 Protein, N-His-KSI (HD388012) expressed in E. coli, spanning Lys2-His90. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q9NUE0 |
| タンパク質長 | Lys2-His90 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 24.82 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | DHHC domain-containing cysteine-rich protein 18, DHHC-18, EC:2.3.1.225, Palmitoyltransferase ZDHHC18, ZDHHC18, Zinc finger DHHC domain-containing protein 18 |
| 背景 | Palmitoyltransferase ZDHHC18 is a ~42 kDa protein. Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK. Acts as a negative regulator of the cGAS-STING pathway be mediating palmitoylation and inactivation of CGAS. May also have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling. 1. Ohno, Y. et al. (2012) Molecular biology of the cell 23, 4543-51. PMID: 23034182 2. Adachi, N. et al. (2016) The Journal of biological chemistry 291, 20232-46. PMID: 27481942 3. Shi, C. et al. (2022) The EMBO journal 41, e109272. PMID: 35438208 |
| 注意事項 | For research use only |
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