Mouse ANGPTL4 Recombinant Protein (C-Fc) (MV344021)

Name: Mouse ANGPTL4 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MV344021
Price: 298 USD
Availability: InStock

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Número de catálogo	MV344021
Descripción	Recombinant Mouse ANGPTL4 Protein, C-Fc (MV344021) expressed in Mammalian Cells, spanning Lys167-Ser410. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	Q9Z1P8
Longitud de proteína	Lys167-Ser410
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	55.79 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ANGPTL4, ANGPTL4 C-terminal chain, ANGPTL4 N-terminal chain, ARP4, Angiopoietin-like protein 4, Angiopoietin-related protein 4, HFARP, Hepatic fibrinogen/angiopoietin-related protein, PGAR
Fondo	Angiopoietin-related protein 4 is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis (Probable). 1. Xu, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 6086-91. PMID: 15837923 2. Desai, U. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 11766-71. PMID: 17609370 3. Gusarova, V. et al. (2018) Nature communications 9, 2252. PMID: 29899519 4. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458 5. Galaup, A. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 18721-6. PMID: 17130448 6. Perdiguero, EG. et al. (2011) The Journal of biological chemistry 286, 36841-51. PMID: 21832056
Nota	For research use only