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Mouse CCL7/MCP-3 Recombinant Protein (N-GST & C-His) (MX155012)

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概要
カタログ番号MX155012
説明
Recombinant Mouse CCL7/MCP-3 Protein, N-GST & C-His (MX155012) expressed in E. coli, spanning Lys40-Pro97. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムE. coli
アクセッション番号Q03366
タンパク質長Lys40-Pro97
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Mus musculus (Mouse)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 34.97 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名C-C motif chemokine 7, CCL7, MCP-3, MCP3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7
背景

C-C motif chemokine 7 is a ~10 kDa protein. Chemotactic factor that plays an important role in immune regulation. Attracts monocytes, eosinophils, basophils, and T-cells to sites of inflammation or infection. Upon binding to various chemokine receptors including CCR1, CCR2, CCR3, and CCR5, facilitates immune cell migration by guiding them to infected tissues. Interacts with CCR2 to facilitate the release of monocytes from the bone marrow into the bloodstream, maintaining monocyte homeostasis. In turn, monocytes recruited to inflamed or injured tissues can differentiate into macrophages or dendritic cells, which are essential for immune defense and tissue repair.

1. Xu, H. et al. (2025) International immunopharmacology 147, 114027. PMID: 39805173
2. Tsou, CL. et al. (2007) The Journal of clinical investigation 117, 902-9. PMID: 17364026
3. Zhu, LP. et al. (2023) Molecular pain 19, 17448069231169373. PMID: 36998150
4. Ford, J. et al. (2018) Frontiers in immunology 9, 3063. PMID: 30671055
注意事項 For research use only
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参考文献
Formula
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