Mouse LAMP-1/CD107a Recombinant Protein (C-His) (MY332021)

Name: Mouse LAMP-1/CD107a Recombinant Protein (C-His)
Brand: abinScience
SKU: MY332021
Price: 298 USD
Availability: InStock

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1mg

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Vista general

Número de catálogo	MY332021
Descripción	Recombinant Mouse CD107a/LAMP1 Protein, C-His (MY332021) expressed in Mammalian Cells, spanning Ala22-Met371. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	P11438
Longitud de proteína	Ala22-Met371
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	41.06 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CD107 antigen-like family member A, CD107a, LAMP-1, LAMP1, Lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1
Fondo	Lysosome-associated membrane glycoprotein 1 is a ~43 kDa protein. Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation, autophagy and cholesterol homeostasis. Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity. Also plays an important role in NK-cells cytotoxicity. Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule. In addition, protects NK-cells from degranulation-associated damage induced by their own cytotoxic granule content. 1. Eskelinen, EL. et al. (2004) Molecular biology of the cell 15, 3132-45. PMID: 15121881 2. Cohnen, A. et al. (2013) Blood 122, 1411-8. PMID: 23847195 3. Heffernan, M. et al. (1989) Cancer research 49, 6077-84. PMID: 2676155
Nota	For research use only

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Referencias

Datasheet

Mouse LAMP-1/CD107a Recombinant Protein (C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

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V₂ (Working Vol.)

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