Mouse LAMP-1/CD107a Recombinant Protein (C-His) (MY332021)

Name: Mouse LAMP-1/CD107a Recombinant Protein (C-His)
Brand: abinScience
SKU: MY332021
Price: 298 USD
Availability: InStock

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100ug
1mg

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Обзор

Каталожный номер	MY332021
Описание	Recombinant Mouse CD107a/LAMP1 Protein, C-His (MY332021) expressed in Mammalian Cells, spanning Ala22-Met371. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	Mammalian cells
Номер доступа	P11438
Длина белка	Ala22-Met371
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Mus musculus (Mouse)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	41.06 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	CD107 antigen-like family member A, CD107a, LAMP-1, LAMP1, Lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1
Фон	Lysosome-associated membrane glycoprotein 1 is a ~43 kDa protein. Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation, autophagy and cholesterol homeostasis. Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity. Also plays an important role in NK-cells cytotoxicity. Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule. In addition, protects NK-cells from degranulation-associated damage induced by their own cytotoxic granule content. 1. Eskelinen, EL. et al. (2004) Molecular biology of the cell 15, 3132-45. PMID: 15121881 2. Cohnen, A. et al. (2013) Blood 122, 1411-8. PMID: 23847195 3. Heffernan, M. et al. (1989) Cancer research 49, 6077-84. PMID: 2676155
Примечание	For research use only

Изображения

Ссылки

Даташит

Mouse LAMP-1/CD107a Recombinant Protein (C-His).pdf

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Formula

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Formula

C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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