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Mouse Integrin alpha L/CD11a Recombinant Protein (C-His) (MB805011)

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Aperçu
Numéro de catalogueMB805011
Description
Recombinant Mouse CD11a/ITGAL Protein, C-His (MB805011) expressed in Mammalian Cells, spanning Lys151-Thr335. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expressionMammalian cells
Numéro d'accèsP24063
Longueur de protéineLys151-Thr335
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspècesMus musculus (Mouse)
Nature Recombinant
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >90% as determined by SDS-PAGE.
Masse moléculaire prédite 24.06 kDa
Forme Lyophilized
Tampon de stockage Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsCD11 antigen-like family member A, CD11A, CD11a, ITGAL, Integrin alpha-L, LFA-1A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
Contexte

Integrin alpha-L is a ~128 kDa protein. Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity.

1. Kaufmann, Y. et al. (1991) Journal of immunology (Baltimore, Md. : 1950) 147, 369-74. PMID: 2051027
2. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055
3. Liu, Z. et al. (2006) Blood 107, 1063-9. PMID: 16234355
4. Jiang, E. et al. (2014) Arteriosclerosis, thrombosis, and vascular biology 34, 34-43. PMID: 24158516
5. Bose, TO. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 2863-72. PMID: 25108025
Note For research use only
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Formula
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Formula
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