Mouse CD169/SIGLEC1 Recombinant Protein (N-His) (MV234012)

Name: Mouse CD169/SIGLEC1 Recombinant Protein (N-His)
Brand: abinScience
SKU: MV234012
Price: 211 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MV234012
Description	Recombinant Mouse CD169/SIGLEC1 Protein, N-His (MV234012) expressed in E. coli, spanning Gly22-Val235. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q62230
Longueur de protéine	Gly22-Val235
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	26.37 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CD169, SIGLEC1, SN, Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec-1
Contexte	Sialoadhesin is a ~182 kDa protein. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response. Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs). In turn, enhances macrophage-to-T-cell transmission of several viruses including murine leukemia virus. Acts as an endocytic receptor mediating clathrin dependent endocytosis. 1. Chang, YC. et al. (2014) Journal of molecular medicine (Berlin, Germany) 92, 951-9. PMID: 24788876 2. Erikson, E. et al. (2015) The Journal of biological chemistry 290, 27345-27359. PMID: 26370074
Note	For research use only

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Mouse CD169/SIGLEC1 Recombinant Protein (N-His).pdf

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