

| Número de catálogo | MV809011 |
|---|---|
| Descripción |
Recombinant Mouse CD273/PD-L2/PDCD1LG2 Protein, C-His (MV809011) expressed in Mammalian Cells, spanning Leu20-Arg219. Purity: >90% by SDS-PAGE.
Highlights
|
| Sistema de expresión | Mammalian cells |
| Número de acceso | Q9WUL5 |
| Longitud de proteína | Leu20-Arg219 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Mus musculus (Mouse) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 25.44 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | B7-DC, B7DC, Butyrophilin B7-DC, CD273, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, PDL2, Programmed cell death 1 ligand 2, Programmed death ligand 2 |
| Fondo | Programmed cell death 1 ligand 2 is a ~27 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production. 1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527 2. Tseng, SY. et al. (2001) The Journal of experimental medicine 193, 839-46. PMID: 11283156 3. Wang, S. et al. (2003) The Journal of experimental medicine 197, 1083-91. PMID: 12719480 4. Lázár-Molnár, E. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 10483-8. PMID: 18641123 |
| Nota | For research use only |
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