

| Número de catálogo | MV217011 |
|---|---|
| Descripción |
Recombinant Mouse CD319/SLAMF7 Protein, C-His (MV217011) expressed in Mammalian Cells, spanning Met1-Gly224. Purity: >90% by SDS-PAGE.
Highlights
|
| Sistema de expresión | Mammalian cells |
| Número de acceso | Q8BHK6 |
| Longitud de proteína | Met1-Gly224 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Mus musculus (Mouse) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 25.64 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CD319, CRACC, CS1, Membrane protein FOAP-12, Novel Ly9, Protein 19A, SLAM family member 7, SLAMF7 |
| Fondo | SLAM family member 7 is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Mediates natural killer (NK) cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on the adapter SH2D1B. 1. Dong, Z. et al. (2009) Nature immunology 10, 973-80. PMID: 19648922 2. Cruz-Munoz, ME. et al. (2009) Nature immunology 10, 297-305. PMID: 19151721 |
| Nota | For research use only |
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