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Mouse ABCG2/CD338 Recombinant Protein (N-His) (MV314012)

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  • 1mg
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Vista general
Número de catálogoMV314012
Descripción
Recombinant Mouse CD338/ABCG2 Protein, N-His (MV314012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoQ7TMS5
Longitud de proteínaAsp35-Pro353
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesMus musculus (Mouse)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Peso molecular predicho 37.31 kDa
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosATP-binding cassette sub-family G member 2, Abcg2, Abcp, Bcrp1, Breast cancer resistance protein 1 homolog, Broad substrate specificity ATP-binding cassette transporter ABCG2, CD338, EC:7.6.2.2, Urate exporter
Fondo

Broad substrate specificity ATP-binding cassette transporter ABCG2 is a ~72 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extrarenal urate excretion. In kidney, it also functions as a physiological exporter of the uremic toxin indoxyl sulfate.

1. Allen, JD. et al. (1999) Cancer research 59, 4237-41. PMID: 10485464
2. Jonker, JW. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 15649-54. PMID: 12429862
3. Allen, JD. et al. (2002) Molecular cancer therapeutics 1, 417-25. PMID: 12477054
4. van Herwaarden, AE. et al. (2007) Molecular and cellular biology 27, 1247-53. PMID: 17145775
5. Takada, T. et al. (2018) Scientific reports 8, 11147. PMID: 30042379
6. Krishnamurthy, P. et al. (2004) The Journal of biological chemistry 279, 24218-25. PMID: 15044468
7. Millán-García, A. et al. (2024) International journal of molecular sciences 25. PMID: 39337371
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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