

| Numéro de catalogue | MV314012 |
|---|---|
| Description |
Recombinant Mouse CD338/ABCG2 Protein, N-His (MV314012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q7TMS5 |
| Longueur de protéine | Asp35-Pro353 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Mus musculus (Mouse) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 37.31 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | ATP-binding cassette sub-family G member 2, Abcg2, Abcp, Bcrp1, Breast cancer resistance protein 1 homolog, Broad substrate specificity ATP-binding cassette transporter ABCG2, CD338, EC:7.6.2.2, Urate exporter |
| Contexte | Broad substrate specificity ATP-binding cassette transporter ABCG2 is a ~72 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extrarenal urate excretion. In kidney, it also functions as a physiological exporter of the uremic toxin indoxyl sulfate. 1. Allen, JD. et al. (1999) Cancer research 59, 4237-41. PMID: 10485464 2. Jonker, JW. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 15649-54. PMID: 12429862 3. Allen, JD. et al. (2002) Molecular cancer therapeutics 1, 417-25. PMID: 12477054 4. van Herwaarden, AE. et al. (2007) Molecular and cellular biology 27, 1247-53. PMID: 17145775 5. Takada, T. et al. (2018) Scientific reports 8, 11147. PMID: 30042379 6. Krishnamurthy, P. et al. (2004) The Journal of biological chemistry 279, 24218-25. PMID: 15044468 7. Millán-García, A. et al. (2024) International journal of molecular sciences 25. PMID: 39337371 |
| Note | For research use only |
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