Mouse DR6/TNFRSF21 Recombinant Protein (C-Fc) (MF685021)

Name: Mouse DR6/TNFRSF21 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MF685021
Price: 298 USD
Availability: InStock

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1mg

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Número de catálogo	MF685021
Descripción	Recombinant Mouse CD358/TNFRSF21 Protein, C-Fc (MF685021) expressed in Mammalian Cells, spanning Gln42-His349. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	Q9EPU5
Longitud de proteína	Gln42-His349
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	61.91 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CD358, DR6, Death receptor 6, TNFRSF21, Tumor necrosis factor receptor superfamily member 21
Fondo	Tumor necrosis factor receptor superfamily member 21 is a ~71 kDa protein. Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. 1. Liu, J. et al. (2001) Immunity 15, 23-34. PMID: 11485735 2. Zhao, H. et al. (2001) The Journal of experimental medicine 194, 1441-8. PMID: 11714751 3. Schmidt, CS. et al. (2003) The Journal of experimental medicine 197, 51-62. PMID: 12515813 4. Mi, S. et al. (2011) Nature medicine 17, 816-21. PMID: 21725297 5. Hu, Y. et al. (2013) Cell death & disease 4, e579. PMID: 23559013
Nota	For research use only

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Datasheet

Mouse DR6/TNFRSF21 Recombinant Protein (C-Fc).pdf

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