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| カタログ番号 | MF685021 |
|---|---|
| 説明 |
Recombinant Mouse CD358/TNFRSF21 Protein, C-Fc (MF685021) expressed in Mammalian Cells, spanning Gln42-His349. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | Mammalian cells |
| アクセッション番号 | Q9EPU5 |
| タンパク質長 | Gln42-His349 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 61.91 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CD358, DR6, Death receptor 6, TNFRSF21, Tumor necrosis factor receptor superfamily member 21 |
| 背景 | Tumor necrosis factor receptor superfamily member 21 is a ~71 kDa protein. Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. 1. Liu, J. et al. (2001) Immunity 15, 23-34. PMID: 11485735 2. Zhao, H. et al. (2001) The Journal of experimental medicine 194, 1441-8. PMID: 11714751 3. Schmidt, CS. et al. (2003) The Journal of experimental medicine 197, 51-62. PMID: 12515813 4. Mi, S. et al. (2011) Nature medicine 17, 816-21. PMID: 21725297 5. Hu, Y. et al. (2013) Cell death & disease 4, e579. PMID: 23559013 |
| 注意事項 | For research use only |
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