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Обзор
Каталожный номерMB984021
Описание
Recombinant Mouse CD9 Protein, N-Fc (MB984021) expressed in Mammalian Cells, spanning Thr110-Ile193. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессииMammalian cells
Номер доступаP40240
Длина белкаThr110-Ile193
ПримененияELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
ВидыMus musculus (Mouse)
Характер Recombinant
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса 37.60 kDa
Форма Lyophilized
Буфер хранения Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия5H9 antigen, CD9, CD9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, MIC3, MRP-1, Motility-related protein, TSPAN29, Tetraspanin-29, Tspan-29, p24
Фон

CD9 antigen is a ~25 kDa protein. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption.

1. Le Naour, F. et al. (2000) Science (New York, N.Y.) 287, 319-21. PMID: 10634790
2. Miyado, K. et al. (2000) Science (New York, N.Y.) 287, 321-4. PMID: 10634791
3. Kaji, K. et al. (2000) Nature genetics 24, 279-82. PMID: 10700183
4. Ishibashi, T. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 96-102. PMID: 14715942
5. Jégou, A. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 10946-51. PMID: 21690351
6. Charrin, S. et al. (2013) Nature communications 4, 1674. PMID: 23575678
7. Takeda, Y. et al. (2003) The Journal of cell biology 161, 945-56. PMID: 12796480
9. Takeda, Y. et al. (2008) The Journal of biological chemistry 283, 26089-97. PMID: 18662991
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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