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| カタログ番号 | MT371012 |
|---|---|
| 説明 |
Recombinant Mouse CDw293/BMPR1B Protein, N-His (MT371012) expressed in E. coli, spanning Lys14-Lys126. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P36898 |
| タンパク質長 | Lys14-Lys126 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 15.01 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | BMP type-1B receptor, BMPR-1B, BMPR1B, Bone morphogenetic protein receptor type-1B, CDw293, EC:2.7.11.30 |
| 背景 | Bone morphogenetic protein receptor type-1B is a ~56 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1. Receptor for GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. 1. Kotzsch, A. et al. (2009) The EMBO journal 28, 937-47. PMID: 19229295 2. Stange, K. et al. (2015) Orphanet journal of rare diseases 10, 84. PMID: 26105076 3. Degenkolbe, E. et al. (2013) PLoS genetics 9, e1003846. PMID: 24098149 |
| 注意事項 | For research use only |
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