Mouse IL-15 Recombinant Protein (C-His) (MW541021)

Name: Mouse IL-15 Recombinant Protein (C-His)
Brand: abinScience
SKU: MW541021
Price: 298 USD
Availability: InStock

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Aviso · Catálogo MW541021 ha sido descontinuado.

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Número de catálogo	MW541021
Descripción	Recombinant Mouse IL15 Protein, C-His (MW541021) expressed in Mammalian Cells, spanning Asn49-Ser162. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	P48346
Longitud de proteína	Asn49-Ser162
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	16.15 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	IL-15, IL15, Interleukin-15
Fondo	Interleukin-15 is a ~18 kDa protein. Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems. Stimulates the proliferation and activation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines. In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection. Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits. Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5. 1. Mattei, F. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 1179-87. PMID: 11466332 2. Khan, IA. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 2103-8. PMID: 8757333 3. Masuda, A. et al. (2000) The Journal of biological chemistry 275, 29331-7. PMID: 10882748 4. Mirghomizadeh, F. et al. (2009) Experimental cell research 315, 3064-75. PMID: 19632221
Nota	For research use only

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Datasheet

Mouse IL-15 Recombinant Protein (C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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