Mouse IL-18 Recombinant Protein (C-Fc) (MC517021)

Name: Mouse IL-18 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MC517021
Price: 298 USD
Availability: InStock

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Número de catálogo	MC517021
Descripción	Recombinant Mouse IL18/IL1F4 Protein, C-Fc (MC517021) expressed in Mammalian Cells, spanning Asn36-Ser192. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	P70380
Longitud de proteína	Asn36-Ser192
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	46.45 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	IFN-gamma-inducing factor, IGIF, IL-1 gamma, IL-18, IL18, IL1F4, Iboctadekin, Interferon gamma-inducing factor, Interleukin-1 gamma, Interleukin-18
Fondo	Interleukin-18 is a ~22 kDa protein. Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. 1. Levy, M. et al. (2015) Cell 163, 1428-43. PMID: 26638072 2. Nowarski, R. et al. (2015) Cell 163, 1444-56. PMID: 26638073 3. Hara, H. et al. (2018) Cell 175, 1651-1664.e14. PMID: 30392956
Nota	For research use only

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Datasheet

Mouse IL-18 Recombinant Protein (C-Fc).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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