Mouse IL-3 Recombinant Protein (N-His) (MY262012)

Name: Mouse IL-3 Recombinant Protein (N-His)
Brand: abinScience
SKU: MY262012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MY262012
Description	Recombinant Mouse IL3 Protein, N-His (MY262012) expressed in E. coli, spanning Asp33-Cys166. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P01586
Longueur de protéine	Asp33-Cys166
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	17.40 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Hematopoietic growth factor, IL-3, IL3, Interleukin-3, MCGF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell-stimulating factor
Contexte	Interleukin-3 is a ~18 kDa protein. Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Also stimulates mature basophils, eosinophils, and monocytes to become functionally activated. In addition, plays an important role in neural cell proliferation and survival. Participates as well in bone homeostasis and inhibits osteoclast differentiation by preventing NF-kappa-B nuclear translocation and activation. Mechanistically, exerts its biological effects through a receptor composed of IL3RA subunit and a signal transducing subunit IL3RB. 1. Jaster, R. et al. (1999) Cellular signalling 11, 331-5. PMID: 10376805 2. Tong, Y. et al. (2020) JCI insight 5. PMID: 31990690 3. Silvennoinen, O. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 8429-33. PMID: 8378315
Note	For research use only

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Mouse IL-3 Recombinant Protein (N-His).pdf

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