Mouse IkB-alpha Recombinant Protein (N-His) (MB155012)

Name: Mouse IkB-alpha Recombinant Protein (N-His)
Brand: abinScience
SKU: MB155012
Price: 211 USD
Availability: InStock

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Número de catálogo	MB155012
Descripción	Recombinant Mouse NFKBIA Protein, N-His (MB155012) expressed in E. coli, spanning Ala63-Asn276. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q9Z1E3
Longitud de proteína	Ala63-Asn276
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	25.76 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	I-kappa-B-alpha, IKBA, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA
Fondo	NF-kappa-B inhibitor alpha is a ~35 kDa protein. Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals. On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. 1. Hatakeyama, S. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 3859-63. PMID: 10097128 2. Spencer, E. et al. (1999) Genes & development 13, 284-94. PMID: 9990853 3. Brown, K. et al. (1995) Science (New York, N.Y.) 267, 1485-8. PMID: 7878466
Nota	For research use only

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Datasheet

Mouse IkB-alpha Recombinant Protein (N-His).pdf

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