Mouse IkB-alpha Recombinant Protein (N-His) (MB155012)

Name: Mouse IkB-alpha Recombinant Protein (N-His)
Brand: abinScience
SKU: MB155012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MB155012
Description	Recombinant Mouse NFKBIA Protein, N-His (MB155012) expressed in E. coli, spanning Ala63-Asn276. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q9Z1E3
Longueur de protéine	Ala63-Asn276
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	25.76 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	I-kappa-B-alpha, IKBA, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA
Contexte	NF-kappa-B inhibitor alpha is a ~35 kDa protein. Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals. On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. 1. Hatakeyama, S. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 3859-63. PMID: 10097128 2. Spencer, E. et al. (1999) Genes & development 13, 284-94. PMID: 9990853 3. Brown, K. et al. (1995) Science (New York, N.Y.) 267, 1485-8. PMID: 7878466
Note	For research use only

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Mouse IkB-alpha Recombinant Protein (N-His).pdf

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