

| Número de catálogo | MD462012 |
|---|---|
| Descripción |
Recombinant Mouse OR51E2 Protein, N-His (MD462012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | Q8VBV9 |
| Longitud de proteína | Ser2-Gly27&Ser75-Ala98&Lys163-Thr200&Tyr291-Thr320 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Mus musculus (Mouse) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 16.14 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, PSGR, Prostate-specific G-protein coupled receptor |
| Fondo | Olfactory receptor 51E2 is a ~35 kDa protein. Olfactory receptor. The activity of this receptor is probably mediated by G-proteins which induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1. Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells. Activated by the short chain fatty acids (SCFA), acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure. 1. Pluznick, JL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4410-5. PMID: 23401498 2. Chang, AJ. et al. (2015) Nature 527, 240-4. PMID: 26560302 3. Torres-Torrelo, H. et al. (2018) Nature 561, E33-E40. PMID: 30258151 |
| Nota | For research use only |
Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский