

| Numéro de catalogue | MD462012 |
|---|---|
| Description |
Recombinant Mouse OR51E2 Protein, N-His (MD462012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q8VBV9 |
| Longueur de protéine | Ser2-Gly27&Ser75-Ala98&Lys163-Thr200&Tyr291-Thr320 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Mus musculus (Mouse) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 16.14 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, PSGR, Prostate-specific G-protein coupled receptor |
| Contexte | Olfactory receptor 51E2 is a ~35 kDa protein. Olfactory receptor. The activity of this receptor is probably mediated by G-proteins which induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1. Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells. Activated by the short chain fatty acids (SCFA), acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure. 1. Pluznick, JL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4410-5. PMID: 23401498 2. Chang, AJ. et al. (2015) Nature 527, 240-4. PMID: 26560302 3. Torres-Torrelo, H. et al. (2018) Nature 561, E33-E40. PMID: 30258151 |
| Note | For research use only |
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