

| Каталожный номер | MD462012 |
|---|---|
| Описание |
Recombinant Mouse OR51E2 Protein, N-His (MD462012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q8VBV9 |
| Длина белка | Ser2-Gly27&Ser75-Ala98&Lys163-Thr200&Tyr291-Thr320 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Mus musculus (Mouse) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 16.14 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, PSGR, Prostate-specific G-protein coupled receptor |
| Фон | Olfactory receptor 51E2 is a ~35 kDa protein. Olfactory receptor. The activity of this receptor is probably mediated by G-proteins which induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1. Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells. Activated by the short chain fatty acids (SCFA), acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure. 1. Pluznick, JL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4410-5. PMID: 23401498 2. Chang, AJ. et al. (2015) Nature 527, 240-4. PMID: 26560302 3. Torres-Torrelo, H. et al. (2018) Nature 561, E33-E40. PMID: 30258151 |
| Примечание | For research use only |
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