

| Numéro de catalogue | MB727011 |
|---|---|
| Description |
Recombinant Mouse S100A4 Protein, C-Fc (MB727011) expressed in Mammalian Cells, spanning Ala2-Lys101. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | Mammalian cells |
| Numéro d'accès | P07091 |
| Longueur de protéine | Ala2-Lys101 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Mus musculus (Mouse) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 39.93 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CAPL, Calvasculin, MTS1, Metastasin, Placental calcium-binding protein, Protein Mts1, Protein S100-A4, S100 calcium-binding protein A4, S100A4 |
| Contexte | Protein S100-A4 is a ~11 kDa protein. Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. 1. Li, ZH. et al. (2010) Molecular biology of the cell 21, 2598-610. PMID: 20519440 2. Kriajevska, MV. et al. (1994) The Journal of biological chemistry 269, 19679-82. PMID: 8051043 3. Grum-Schwensen, B. et al. (2010) Cancer research 70, 936-47. PMID: 20103644 |
| Note | For research use only |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский