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Mouse Serpinb1a Recombinant Protein (N-His) (MD634012)

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  • 1mg
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Vista general
Número de catálogoMD634012
Descripción
Recombinant Mouse Serpinb1a Protein, N-His (MD634012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoQ9D154
Longitud de proteínaMet1-Pro379
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesMus musculus (Mouse)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosLeukocyte elastase inhibitor A, Serine protease inhibitor EIA, Serpin B1a, Serpinb1, Serpinb1a
Fondo

Leukocyte elastase inhibitor A is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of granzyme H.

1. Benarafa, C. et al. (2007) The Journal of experimental medicine 204, 1901-9. PMID: 17664292
2. Benarafa, C. et al. (2011) Journal of leukocyte biology 90, 21-9. PMID: 21248149
3. Benarafa, C. (2011) Methods in enzymology 499, 135-48. PMID: 21683252
4. Choi, YJ. et al. (2019) Nature immunology 20, 276-287. PMID: 30692621
5. Benarafa, C. et al. (2002) The Journal of biological chemistry 277, 42028-33. PMID: 12189154
6. El Ouaamari, A. et al. (2016) Cell metabolism 23, 194-205. PMID: 26701651
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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