Mouse TFAM Recombinant Protein (N-His) (MX990012)

Name: Mouse TFAM Recombinant Protein (N-His)
Brand: abinScience
SKU: MX990012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MX990012
Description	Recombinant Mouse TFAM Protein, N-His (MX990012) expressed in E. coli, spanning Ser43-Ile200. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P40630
Longueur de protéine	Ser43-Ile200
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	20.73 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Mitochondrial transcription factor 1, MtTF1, TCF-6, TCF6, TCF6L2, TFAM, Transcription factor 6, Transcription factor 6-like 2, Transcription factor A, mitochondrial, mtTFA
Contexte	Transcription factor A, mitochondrial is a ~27 kDa protein. Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. 1. Larsson, NG. et al. (1998) Nature genetics 18, 231-6. PMID: 9500544 2. Kaufman, BA. et al. (2007) Molecular biology of the cell 18, 3225-36. PMID: 17581862
Note	For research use only

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Mouse TFAM Recombinant Protein (N-His).pdf

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