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| カタログ番号 | MP583012 |
|---|---|
| 説明 |
Recombinant Mouse TRPV6/ECaC2 Protein, N-His (MP583012) expressed in E. coli, spanning Phe107-Pro366. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q91WD2 |
| タンパク質長 | Phe107-Pro366 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 31.30 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CaT-L, CaT-like, CaT1, Calcium transport protein 1, ECAC2, ECaC2, Epithelial calcium channel 2, TRPV6, Transient receptor potential cation channel subfamily V member 6, TrpV6 |
| 背景 | Transient receptor potential cation channel subfamily V member 6 is a ~87 kDa protein. Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine. Important for normal Ca(2+) ion homeostasis in the body, including bone and skin. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. 1. Hoenderop, JG. et al. (2003) The EMBO journal 22, 776-85. PMID: 12574114 2. Voets, T. et al. (2003) The Journal of general physiology 121, 245-60. PMID: 12601087 3. Hirnet, D. et al. (2003) Cell calcium 33, 509-18. PMID: 12765696 4. Voets, T. et al. (2004) The Journal of biological chemistry 279, 15223-30. PMID: 14736889 5. Lambers, TT. et al. (2004) The Journal of biological chemistry 279, 28855-61. PMID: 15123711 6. Bianco, SD. et al. (2007) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 22, 274-85. PMID: 17129178 7. Woudenberg-Vrenken, TE. et al. (2012) American journal of physiology. Gastrointestinal and liver physiology 303, G879-85. PMID: 22878123 |
| 注意事項 | For research use only |
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