Mouse UCP1 Recombinant Protein (N-GST & C-His) (MB024012)

Name: Mouse UCP1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: MB024012
Price: 211 USD
Availability: InStock

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Número de catálogo	MB024012
Descripción	Recombinant Mouse UCP1 Protein, N-GST & C-His (MB024012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P12242
Longitud de proteína	Pro33-Lys73&Thr134-Thr178&Val233-Ala266
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Mitochondrial brown fat uncoupling protein 1, Slc25a7, Solute carrier family 25 member 7, Thermogenin, UCP 1, Ucp, Ucp1
Fondo	Mitochondrial brown fat uncoupling protein 1 is a ~33 kDa protein. Mitochondrial transporter that functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Regulates the production of reactive oxygen species/ROS by mitochondria. 1. Fedorenko, A. et al. (2012) Cell 151, 400-13. PMID: 23063128 2. Feldmann, HM. et al. (2009) Cell metabolism 9, 203-9. PMID: 19187776 3. Chouchani, ET. et al. (2016) Nature 532, 112-6. PMID: 27027295 4. Enerbäck, S. et al. (1997) Nature 387, 90-4. PMID: 9139827 5. Dlasková, A. et al. (2010) Biochimica et biophysica acta 1797, 1470-6. PMID: 20416274 6. Oelkrug, R. et al. (2010) The Journal of biological chemistry 285, 21961-8. PMID: 20466728
Nota	For research use only

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Referencias

Datasheet

Mouse UCP1 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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