Anti-Human PD-L1 & 4-1BB/TNFRSF9/CD137 Bispecific Reference Antibody (Acasunlimab, RUO) (HV974136)

Name: Anti-Human PD-L1 & 4-1BB/TNFRSF9/CD137 Bispecific Reference Antibody (Acasunlimab, RUO)
Brand: abinScience
SKU: HV974136
Price: 400 USD
Availability: InStock

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100ug
1mg
5mg
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SDS

Vista general

Número de catálogo	HV974136
Descripción	Acasunlimab (HV974136) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1;Lambda;Kappa
Objetivo	B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, 4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9NZQ7 & Q07011
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Bispecific, BNT-311, DuoBody-PD-L1x4-1BB, GEN-1046, 2253937-12-9
Fondo	Acasunlimab (GEN1046) is a bispecific antibody (bsAb) targeting PD-L1 and 4-1BB. Acasunlimab enhances T-cell and NK-cell function through conditional 4-1BB stimulation while constitutively blocking the PD-1/PD-L1 inhibitory axis. Acasunlimab can be used in research of cancer.
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Bioactivity

Detects CD137/TNFRSF9/4-1BB in indirect ELISAs.
Bioactivity

Detects CD274/PD-L1/B7-H1 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Acasunlimab.

Referencias

Datasheet

Anti-Human PD-L1 & 4-1BB/TNFRSF9/CD137 Bispecific Reference Antibody (Acasunlimab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

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