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Anti-Human EpCAM/TROP1 Reference Antibody (Adecatumumab, RUO) (HB104026)

Anti-Human EpCAM/TROP1 Reference Antibody (Adecatumumab, RUO)
Anti-Human EpCAM/TROP1 Reference Antibody (Adecatumumab, RUO)
Anti-Human EpCAM/TROP1 Reference Antibody (Adecatumumab, RUO)
Anti-Human EpCAM/TROP1 Reference Antibody (Adecatumumab, RUO)
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  • 概要

  • イメージ

  • 参考文献

  • データシート

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概要
カタログ番号HB104026
説明
Adecatumumab (HB104026) is a research-grade recombinant antibody targeting CD326. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FCM, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG1-nd
ターゲット Adenocarcinoma-associated antigen, CD326, Cell surface glycoprotein Trop-1, EGP, EGP314, EPCAM, Ep-CAM, Epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, GA733-2, KS 1/4 antigen, KSA, M1S2, M4S1, MIC18, Major gastrointestinal tumor-associated protein GA733-2, TACSTD1, TROP1, Tumor-associated calcium signal transducer 1, hEGP314
エンドトキシンレベル < 10 EU/mg
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P16422
形態 Liquid
保存バッファー 0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名MT201, 503605-66-1
背景

Epithelial cell adhesion molecule (CD326/EPCAM) is a ~34 kDa protein. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
イメージ
  • Anti-Human EpCAM/TROP1 Reference Antibody (Adecatumumab, RUO)

    Bioactivity

    Detects Human CD326/EPCAM in indirect ELISAs.

  • Anti-Human EpCAM/TROP1 Reference Antibody (Adecatumumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Adecatumumab

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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