

| Número de catálogo | HW564116 | ||||
|---|---|---|---|---|---|
| Descripción |
Research Grade afivastobart (HW564116) is a human monoclonal antibody. Suitable for Human.
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| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| Especie huésped | Human | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1, kappa | ||||
| Nivel de endotoxinas | < 10 EU/mg | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | P49961 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Ectonucleoside triphosphate diphosphohydrolase 1 (CD39/ENTPD1) is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. 1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 8529670 2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624 3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 8955160 4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251 | ||||
| Nota | For research use only. |




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