Anti-Human MMP-9 Reference Antibody (Andecaliximab, RUO) (HB945016)

Name: Anti-Human MMP-9 Reference Antibody (Andecaliximab, RUO)
Brand: abinScience
SKU: HB945016
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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25mg
50mg
100mg

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Referencias
Datasheet
SDS

Vista general

Número de catálogo	HB945016
Descripción	Andecaliximab (HB945016) is a research-grade recombinant antibody targeting Matrix metalloproteinase-9. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Chimeric
Clonalidad	Monoclonal
Isotipo	IgG4-kappa
Sistema de expresión	Mammalian cells
Objetivo	Matrix metalloproteinase-9, CLG4B, GELB, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, MMP9, MMP-9
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P14780
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	GS-5745, 1518996-49-0
Fondo	Matrix metalloproteinase-9 (MMP9) is a ~78 kDa protein. Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-\|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. 1. Takino, T. et al. (2003) Oncogene 22, 4617-26. PMID: 12879005 2. Tschesche, H. et al. (1992) Matrix (Stuttgart, Germany). Supplement 1, 245-55. PMID: 1480034 3. Wilhelm, SM. et al. (1989) The Journal of biological chemistry 264, 17213-21. PMID: 2551898 4. Jeon, S. et al. (2020) Circulation 142, 1736-1751. PMID: 32883094
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

Imágenes

SEC-HPLC

SEC-HPLC detection for Research Grade Andecaliximab.
Bioactivity

Detects MMP9 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Andecaliximab.

Referencias

Datasheet

Anti-Human MMP-9 Reference Antibody (Andecaliximab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

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