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| カタログ番号 | VK689016 | ||||
|---|---|---|---|---|---|
| 説明 |
Anivovetmab (VK689016) is a research-grade recombinant antibody targeting Capsid protein VP2. Produced in mammalian cells with native-like glycosylation.
Highlights
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| 種反応性 | Canine parvovirus type 2 (CPV2) | ||||
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| 宿主種 | Canine | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2, kappa | ||||
| 発現システム | Mammalian cells | ||||
| ターゲット | Capsid protein VP2 | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% purity as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P61826 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 別名 | KIND030, KIND-030, KIND030, 2370896-63-0 | ||||
| 背景 | Capsid protein VP2 is a ~64 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s). | ||||
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anivovetmab
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