





| Каталожный номер | HB209156 | ||||
|---|---|---|---|---|---|
| Описание |
Ansipastobart (HB209156) is a research-grade recombinant antibody targeting CD73. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Реактивность видов | Human | ||||
| Применения | ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB | ||||
| Хозяинский вид | Human | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG1-lambda2 | ||||
| Проверенные приложения | WB | ||||
| Цель | 5'-NT, 5'-deoxynucleotidase, 5'-nucleotidase, CD73, EC:3.1.3.35, EC:3.1.3.5, EC:3.1.3.89, EC:3.1.3.91, EC:3.1.3.99, Ecto-5'-nucleotidase, IMP-specific 5'-nucleotidase, NT5, NT5E, NTE, Thymidylate 5'-phosphatase | ||||
| Уровень эндотоксинов | < 10 EU/mg | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P21589 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Альтернативные названия | 2829250-32-8 | ||||
| Фон | 5'-nucleotidase (CD73/NT5E) is a ~63 kDa protein. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN. 1. Garavaglia, S. et al. (2012) The Biochemical journal 441, 131-41. PMID: 21933152 2. Heuts, DP. et al. (2012) Chembiochem : a European journal of chemical biology 13, 2384-91. PMID: 22997138 3. Knapp, K. et al. (2012) Structure (London, England : 1993) 20, 2161-73. PMID: 23142347 4. Fausther, M. et al. (2014) PloS one 9, e98568. PMID: 24887587 5. Scaletti, E. et al. (2021) Purinergic signalling 17, 693-704. PMID: 34403084 | ||||
| Примечание | For research use only. Not suitable for clinical or therapeutic use. | ||||
| Isotype Control | Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107) |

SDS-PAGE for Research Grade Ansipastobart

Detects recombinant CD73 (Catalog No: HB209011) in indirect ELISA.

Western blot analysis was performed using anti-CD73 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD73 (Catalog No: HB209011)
Lane 2: Negative control




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