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Anti-Candida auris β-1, 3 glucans Reference Antibody (2G8, RUO) (JN903016)

Anti-Candida auris β-1, 3 glucans Reference Antibody (2G8, RUO)
Anti-Candida auris β-1, 3 glucans Reference Antibody (2G8, RUO)
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Vista general
Número de catálogoJN903016
Reactividad de especiesCandida auris
AplicacionesELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clon2G8
Actividad biológica β-D-glucan dissolved in DMSO but not water inhibits MCF-7 cell proliferation in a concentration-dependent manner as measured by BrdU incorporation with an IC 50 of ~164 ug/mL. β-D-glucan dissolved in DMSO inhibits tamoxifen/endocrine-resistant LCC9 and LY2 cell proliferation with IC 50 values of 4.6 and 24.2 ug/mL, respectively [3].
Sistema de expresión Mammalian cells
Objetivo Cryptococcus neoformans, β-D-glucan, Beta-D-Glucan, beta-Glucan, β-1, 3 glucans
Nivel de endotoxinas < 10 EU/mg
Pureza >95% purity as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso ChEBI: 28793, 9041-22-9
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Referencias 1. Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. [JN903016]
2. Gani A, et al. β-d-glucan as an enteric delivery vehicle for probiotics. Int J Biol Macromol. 2018;106:864-869. [JN903016]
3. Jafaar ZM, et al. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 2014;44(4):1365-1375. [JN903016]
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Candida auris β-1, 3 glucans Reference Antibody (2G8, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Candida auris β-1,3 glucans Antibody (2G8).

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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