

| Каталожный номер | VK617106 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-HIV1 gp120/Glycoprotein 120 Antibody (mD1.22) (VK617106) is a research-grade recombinant antibody targeting CD4. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Реактивность видов | Human immunodeficiency virus type 1 (HIV-1) | ||||
| Применения | ELISA, Functional assay, Research in vivo | ||||
| Хозяинский вид | Human | ||||
| Клоональность | Monoclonal | ||||
| Изотип | Fusion - [CD4 (LFA3, lymphocyte function associated antigen 3)]2 - IGHG1 Fc (Fragment constant) | ||||
| ID клона | mD1.22 | ||||
| Система экспрессии | Mammalian cells | ||||
| Цель | T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, CD4 | ||||
| Уровень эндотоксинов | < 10 EU/mg | ||||
| Чистота | >95% purity as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P01730 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | T-cell surface glycoprotein CD4 (gp120/Glycoprotein 120) is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. | ||||
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |




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